Master’s student Bernardo Lannes’ seminar addressed the effects of early exposure to polystyrene microplastics (PS-MPs) and their impact on glucose metabolism in zebrafish. The fish were exposed to PS-MPs from the embryonic stage until 27 days of age, and the early life stages were analyzed, as well as the individuals in adulthood. It was observed that the exposed animals showed greater weight and length, accumulation of MPs in tissues, and a tendency towards increased fasting blood glucose. Furthermore, it was seen that animals exposed to a diet with a caloric surplus and PS-MPs showed a greater tendency to alter these parameters. Molecular analyses also revealed alterations in gene expression of genes related to insulin signaling and oxidative stress. These results suggest a possible association between early exposure to MPs and long-term metabolic alterations.